Abstract
In its course, primary Sjӧgren's syndrome marks an increased risk for developing lymphomas. Compared to healthy population, this risk can reach a 44-fold higher frequency. In the case of a relatively calm course of the disease, a "break" in the clinical picture may occur and the manifestations of malignant lymphoma may develop. However, there are clinical and laboratory abnormalities of varying duration, which, with their summation over time, shorten the path to malignant lymphoproliferation. The identification of groups of patients at an increased risk for developing lymphomas and their follow-up is the basis of the personalized approach in patients with Sjӧgren's syndrome.
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