Rheumatology (Bulgaria), Volume 33, Issue 4 (2025) features original research articles, comprehensive reviews, and a clinical case report covering key domains in modern rheumatology. The issue addresses vascular involvement in spondyloarthritis, interventional approaches in osteoarthritis, and the evolving role of cytokines in disease pathogenesis and therapy.
Additional contributions explore emerging concepts in osteoarthritis biology and present a clinically relevant case of overlapping rheumatic diseases. Together, these articles highlight current advances, unresolved challenges, and the translational direction of the field.